The Auspitz sign—pinpoint bleeding when outer scales are removed from psoriatic plaques—is a classic finding in psoriasis, along with several more or less. Synonyms: Auspitz sign, “Phänomen des blutigen Taus” (“phenomenon of bloody dew”). Definition of the phenomenon: The Auspitz phenomenon is the. This page includes the following topics and synonyms: Auspitz Sign.

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Long term use Increased risk of skin cancer Premature aging of the skin. We list the most important complications. Skin atrophy with chronic use Risk: Erythemascaling 2—6 days following onset, lesions of underlying diseasepruritus.

Scalp Extensor surfaces of joints kneeselbows Back.

Eign surfaces of extremities e. Increased proliferatio n of keratinocytes Acanthosis: Find hundreds of Learning Cards covering all clinical subjects Practice answering thousands of USMLE-formatted multiple choice questions in the Qbank Explore concepts in depth with interactive images, videos and charts Fill knowledge gaps with the help of supportive features and an analysis of your progress.

Psoriasis – Knowledge for medical students and physicians

Sifn fluid accumulation leads to the formation of intraepidermal vesicles. Psoriasis is associated with depression and a decreased quality of life. The typical lesions are sharply demarcated, erythematousscaly, pruritic plaqueswhich occur most often on the extensor surfaces of the knees and elbowsbut may also affect the scalp and back.


Epidemiological data refers to the US, unless otherwise specified. If first-degree relatives of patients with psoriasis have joint problems, psoriatic arthritis should be considered!

Auspitz’s sign – Wikipedia

The mechanism causing the immune response is not yet well understood. Differential diagnosis of scaling Lesion Distribution Psoriasis Clearly demarcatederythematous plaques with silvery scalingpruritus Scalp Extensor surfaces of joints kneeselbows Back Atopic dermatitis Poorly demarcatedeczemawhite scales, severe xerosis and pruritus Extensor surfaces of extremities e. Topical medication as combination therapy Add systemic agents as needed methotrexateretinoidcyclosporine Phototherapy.

The disease manifests following exposure to various triggers e.

Clinical science Psoriasis is a common chronic inflammatory skin disorder affecting individuals with an underlying genetic predisposition.

Clearly demarcated, erythematous plaquesgreasy-looking yellow scales. Prepare and succeed on your medical exams. Typically palms and soles Islands of unaffected skin sparing Follicular keratosis.

Generalized erythema Scaling initially in flexural creases. As psoriasis presents with several subtypes, the size, location, and severity of the lesions vary. Lifelong diseaseusually benign Patients may experience remissions of varying lengths; acute episodes of exacerbation possible.

Physical stimuli or skin injury e. Cutaneous variants Plaque psoriasis: Topical treatment Adverse effects Topical steroids Skin atrophy with chronic use Risk: Poorly demarcatedeczemawhite scales, severe xerosis and pruritus. Other common clinical findings include involvement of the nails e.


Avoidance of nicotine and alcohol Regular physical activity. Clearly demarcatederythematous plaques with silvery scalingpruritus.

Auspitz sign is not sensitive or specific for psoriasis.

Psoriasis is a common chronic inflammatory skin disorder affecting individuals with an underlying genetic predisposition. Liver and lung toxicity. Disseminated, plaques with orange-pink scaleshyperkeratosis aauspitz, erythroderma.

Medical therapy Mild to moderate psoriasis Moderate to severe psoriasis Severe psoriasis First-line: The diagnosis is based primarily on clinical findings, but may also be confirmed with tests e. Etanerceptadalimumabinfliximab. The selection is not exhaustive. Ultraviolet light is effective in treating dermatological conditions, as it has antiproliferative effects slowing keratinization and anti-inflammatory effects inducing apoptosis of pathogenic T cells on the skin.

It appears that JavaScript is disabled in your browser. Rarely correlated with HLA. Laboratory tests In case of psoriatic arthritis: Epidermal infiltration by lymphocytes is common. Increased risk of other comorbidities Metabolic syndrome Cardiovascular diseases hypertensioncoronary heart diseasemyocardial infarctionstroke Chronic kidney disease References: Mild psoriasis is treated with topical agents such as steroids, whereas moderate to severe disease requires systemic therapy e.