PDF | Phytochemical studies on the aerial parts of Prangos uloptera, an endemic Iranian species of the genus Prangos, yielded five coumarins. Keywords: Prangos uloptera, Apiaceae, Umbelliferae, coumarin, Umbelliferae) is an endemic Iranian species of the genus Prangos that comprises ca. Antimicrobial and antioxidant activities of coumarins from the roots of Ferulago campestris (Apiaceae). Basile A(1), Sorbo S, Spadaro V, Bruno.

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Penile nitric oxide levels were also promoted, a mechanism that may enhance vasodilation and erectile function. Effect of total glucosides of Centella asiatica on antagonizing liver fibrosis induced by dimethylnitrosamine in rats.

The method used by Takao et al. J Eur Acad Dermatol Venereol. Both annuals and perennial species occur ccoumarin this family, and even among the long-lived perennials, such as the Azorella that occurs in the Antarctic as a broad flat mat surviving for hundreds of years in harsh conditions, tough mineralization and a woody habit does not occur. Vasodilator effects of visnagin in isolated rat vascular smooth muscle. A tincture preparation of Petroselinum has been shown to reduce excessive gastric secretions and offer protective effects to the gastric mucosa in animals predisposed to ulcers and other lesions.

THE APIACEAE FAMILY – Medicinal Plant Research Summary

Dicoumarol is structurally similar to Vitamin K and acts as an antagonist, competing with Vitamin K and reducing the effects of this blood clotting vitamin to promote the clotting factors VII, IX, and X. The occurrence of deltoin 4 within the genus Prangos is rather restricted mainly to P. Other studies have reported melanocyte stimulation from the use of khella. An inhaler version of this medication is marketed under the trade name of Intal.

Angelica promotes numerous natural defense mechanisms including increased ability of the blood cells to directly engulf disease producing invaders, and ability of the cells to secrete substances that enhance immunity. When content is low, but chronically ingested, such as by livestock over a period of time, fetal malformations are reported. Other researchers measured alkaline phosphatase, osteocalcin, osteopontin, type I collagen activity, and osteoblastic proliferation following dosing with osthole.


Cnidium has been used traditionally in China to improve male sexual function. Please help to improve this article by introducing more precise citations. Anti-allergic effects of cnidii monnieri fructus dried fruits of Cnidium monnieri and its major component, osthol. This is likely the same mechanism by which Ammi visnaga is bronchodilating being valuable for asthma and spastic coughing.

Celery and parsnips, two commonly consumed Apiacea family vegetable consistently contain photoactive coumarin compounds, particularly xanthotoxin and bergapten. Protective effect of Umbelliferone on membranous fatty acid composition in streptozotocin-induced diabetic rats.

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The anti-cancer effects include the inhibition of cell proliferation and the induction of apoptosis. Investigation of intracellular signalling events mediating the apiacae of action of 7-hydroxycoumarin and 6-nitrohdroxycoumarin in human renal cells. The enxyme flavone synthase has been found to be high in Apiaceae plants and is looked at, by evolutionary coymarin as a marker the evolutionary process. Cholinergic basis of memory-strengthening effect of Foeniculum vulgare Linn. Many women have found Angelica to improve their menstrual cramps.

Foeniculum also acts as a deterent to mosquitoes. This section does not cite any sources.

Hemlock alkaloids from Socrates to poison aloes. Khellin has been shown to penetrate the stratum corneum with topical application and inotophoresis increases the concentration in the skin. Furocoumarin are also active in the liver apiqceae have a low therapeutic window due to toxicity concerns. A bioassay using Artemia salina for detecting phototoxicity of plant coumarins. Bioavailability of apigenin from apiin-rich parsley in humans. Coumarins from Cnidium monnieri L. Furthermore, the plants are rarely succulent, juicy or rich in sap.

There have been 4 cases summarized from European literature of methemoglobinermia in infants fed fennel purees.

A review of the microcirculation in skin in patients with chronic venous insufficiency: Researchers noted improved phagocytosis, total leukocyte and differential leukocyte counts compared to cortisone, without the inhibitory effects on the bone marrow. Researchers believe that cholesterol is diminished via enhanced biliary excretion, not by interference with the reductase enzymes. Treatment of vitiligo with local khellin and UVA: Ammi visnaga tea has been shown to possess a significant hypoglycemic effect in diabetic rats.


Vegetables in the Apicacea family include celery, fennel, parsely, carrots, and parsnips are noted to be high in polyacetylenes including falcarinol, falcarinidiol, and panaxudiol. Traditionally groups within the family have been delimited largely based on fruit morphologyand the results from this have not been congruent with the more recent molecular phylogenetic analyses.

The dermal penetration of topically applied xanthotoxin has been investigated.

Apiaceae – Wikipedia

coumain Animal studies have shown Angelica to have a general analgesic and anti-inflammatory effect. A comparative studying between osthole and estradiol on bone density of ovarectomized rats showed both estradiol and osthole to protect from cancellous bone loss compared to controls, while only estradiol prevented uterus atrophy. Since the amounts are small, it is not commonly apiacdae that aiaceae of reasonable dietary amounts of these vegetables causes photosensitivity. The early stages of some forms of cutaneous T-cell lymphoma have been shown to respond to psoralen consumption combined with ultraviolet light exposure.

The polyphenol contentin foods is sometimes measured in terms of gallic acid equivenlency GAE. The infants become cyanotic and responded to methylene blue therapy making full recoveries.

The topical application of khellin in combination with UV or natural sunlight may be effective for chronic skin lesions.

Topical khellin and natural sunlight in the outpatient treatment of recalcitrant palmoplantar pompholyx: Visnagin may also interact with phosphodiasterase enzymes having a vasorelaxing effect.

Osthol, but not xanthotoxin has been noted to have activity at TRH receptors in rats. Histological evaluation demonstrated osthole to dramtically reduce lipid accumulation in the liver in both treated groups over controls Patients with hepatitis C have an increased risk for developing Hepatocellular carcinoma.

We can observe this affinity with the air, for one, it the physical presentation of the plant. The aromas are not highly rich or intoxicating like Rose, Apiiaceae, or citrus. Animal studies on a coumarin containing Melilotus officinalis was shown to reduce acute vascular inflammation.