Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Enablex (darifenacin). mg and 15 mg darifenacin (as darifenacin hydrobromide). Muscarinic M3 This leaflet is part III of a three-part Product. Monograph. Enablex (darifenacin) is used to treat symptoms of overactive bladder. Includes Enablex side effects, interactions and indications. See also: Drug Interactions ( in more detail).

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Therapy should be aimed at reversing the anticholinergic symptoms under careful medical supervision. The following information includes only the average doses of this medicine.

This medicine may make you sweat less, causing your body temperature to increase. The initial products of the hydroxylation and N-dealkylation pathways are major circulating metabolites but none contribute significantly to the overall clinical effect of darifenacin. They can be taken with or without food, and must be swallowed whole and not chewed, divided or crushed. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

However, caution should be exercised. When co-administered with moderate CYP3A4 inhibitors such as erythromycin, clarithromycin, telithromycin, fluconazole and grapefruit juice, the recommended starting dose of darifenacin should be 7. Do not break, crush, or chew it. Subscribe to receive email notifications whenever new articles are published. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.


Oedema peripheral, asthenia, enabled oedema, oedema. Available for Android and iOS devices. Reporting suspected adverse reactions after authorisation of the medicinal product is important. No dose adjustment is required in patients with mild hepatic impairment Child Pugh A. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Tell your ihsert if you are breast-feeding a baby. Call your doctor if you get severe stomach pain or become constipated.

Using this medicine with any of the following medicines is not recommended. Pregnancy Pcakage are limited amount of data from the use of darifenacin in pregnant women.

Warfarin Standard inserf prothrombin time monitoring for warfarin should be continued. A single copy of these materials may be reprinted for noncommercial personal use only. These side effects may go away during treatment as your body adjusts to the medicine.

This medicine may cause dry mouth. The increase in digoxin exposure could be caused by competition between darifenacin and digoxin for P-glycoprotein.

Darifenacin (Oral Route) Side Effects – Mayo Clinic

For this medicine, the following should be considered:. Each tablet contains 7. Micromedex US Brand Name Enablex Descriptions Darifenacin is used to treat symptoms of an overactive bladder, such as incontinence loss of bladder control or a frequent need to urinate. No dose adjustment is required in patients with impaired renal function. This medicine may cause blurred vision and may impair your thinking or reactions.

The effects of darifenacin on the metabolism of CYP2D6 substrates are mainly clinically relevant for CYP2D6 substrates which are individually dose titrated. Mayo Clinic does not endorse any of the third party products and services advertised.


Emselex 7.5mg prolonged release tablets

However the data available do not indicate that darifenacin changes either midazolam clearance or bioavailability. It is not known whether darifenacin is excreted in human milk. Pregnancy and breastfeeding warnings in more detail. To bookmark a medicine you must sign up and log in. Appropriate studies have not been performed on the relationship of age to the effects of darifenacin in the pediatric population. There are limited amount of data from the use of darifenacin in pregnant women.

It is not known whether this selectivity for the M3 receptor translates into any clinical advantage when treating symptoms of overactive bladder syndrome.

Be sure to ask your doctor about pafkage you do not understand. The presence of other medical problems may affect the use of this medicine. Find out more here.

In patients receiving substances that are moderate CYP3A4 inhibitors, such as fluconazole, grapefruit juice and erythromycin, the recommended starting dose is 7. Always consult your healthcare provider to ensure the information displayed on this pacage applies to enableex personal circumstances. The pharmacokinetics of darifenacin at steady state are dose-dependent, due to saturation of the CYP2D6 enzyme. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.